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Postdoc Position Application

Job Description
Research in the Brambati Lab focuses on understanding the molecular mechanisms of DNA double-strand break repair and their impact on genome integrity and evolution. We investigate how alternative repair pathways, particularly microhomology-mediated end-joining and RNA-templated DSB repair, contribute to chromosome stability, genome plasticity, and cellular adaptation. Our work combines molecular biology, genomics, and biochemical approaches to characterize these non-canonical repair mechanisms across different cellular contexts, including mitosis and post-mitotic cells. We aim to elucidate the physiological roles of these pathways in genome maintenance, their evolutionary significance, and their implications in human disease.

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